Scientific References

1. Pascal Mock (2024). Live births after bioengineering-assisted in utero embryo culture. Journal of Reproductive Biotechnology and Biomedical Sciences, 13, 10-18.

2. Agarwal A., Maldonado Rosas I., Anagnostopoulou C., Cannarella R., Boitrelle F., Munoz L.V., Finelli R., Durairajanayagam D., Henkel R., Saleh R. (2022). Oxidative Stress and Assisted Reproduction: A Comprehensive Review of Its Pathophysiological Role and Strategies for Optimizing Embryo Culture Environment. Antioxidants, 11(3), 477.

3. Bartolacci A., de Girolamo S., Fraire-Zamora J.J., Pagliardini L., Papaleo E. (2025). The eternal dilemma: are embryos better nurtured in utero or in vitro? Reproductive BioMedicine Online, 51(5), 105103.

4. Blockeel C., Mock P., Verheyen G., Bouche N., Le Goff P., Heyman Y., Wrenzycki C., Höffmann K., Niemann H., Haentjens P., de Los Santos M.J., Fernandez-Sanchez M., Velasco M., Aebischer P., Devroey P., Simón C. (2009). An in vivo culture system for human embryos using an encapsulation technology: a pilot study. Human Reproduction, 24(4), 790-796.

5. Kermack A.J., Finn-Sell S., Cheong Y.C., Brook N., Eckert J.J., Macklon N.S., Houghton F.D. (2015). Amino acid composition of human uterine fluid: association with age, lifestyle and gynaecological pathology. Human Reproduction, 30(4), 917-924.

6. Ramos-Ibeas P., Gimeno I., Cañón-Beltrán K., Gutiérrez-Adán A., Rizos D., Gómez E. (2020). Senescence and Apoptosis During in vitro Embryo Development in a Bovine Model. Frontiers in Cell and Developmental Biology, 8, 619902.

7. Sciorio R., Tramontano L., Gullo G., Fleming S. (2025). Association Between Human Embryo Culture Conditions, Cryopreservation, and the Potential Risk of Birth Defects in Children Conceived Through Assisted Reproduction Technology. Medicina, 61(7), 1194.

8. Ménézo Y., Lichtblau I., Elder K. (2013). New insights into human pre-implantation metabolism in vivo and in vitro. Journal of Assisted Reproduction and Genetics, 30(3), 293-303.

9. Sebastian Canovas, Elena Ivanova, Raquel Romar, Soledad Garcı a-Martınez, Cristina Soriano-Ubeda, Francisco A Garcıa-Vazquez, Heba Saadeh, Simon Andrews, Gavin Kelsey, Pilar Coy(2017). DNA methylation and gene expressionchanges derived from assistedreproductive technologies can bedecreased by reproductive fluids

10. Christine Wrenzycki (2018). Gene expression analysis and in vitro production proceduresfor bovine preimplantation embryos: Past highlights, presentconcepts and future prospects

11. Mariagrazia Paonessa (2021). Genetic causes of preimplantation embryo developmental failure